Omarigliptin (formerly known as MK-3102; MK3102) is a potent, selective, oral and long-acting inhibitor of DPP-4 (dipeptidyl peptidase 4) with antidiabetic effects.

Trelagliptin (formerly also known as SYR-472; trade name Zafatek) is a potent, highly selective, long-acting DPP-4 (dipeptidyl peptidase-4) inhibitor with potential anti-hyperglycemic activity.

Trelagliptin succinate (also known as SYR-472 succinate) is a potent, highly selective, long-acting DPP-4 (dipeptidyl peptidase-4) inhibitor under development by Takeda for the treatment of type 2 diabetes (T2D)..

Saxagliptin (formerly also known as BMS-477118; brand name: Onglyza) is a potent, orally bioactive, selective and reversible DPP-4 (dipeptidyl peptidase-4) inhibitor with potential anti-hyperglycemic activity.

Sitagliptin (formerly also known as MK-431; trade name Januvia), an antihyperglycemic agent and aantidiabetic drug, is a potent, orally bioavailable inhibitor of DPP-IV (dipeptidyl peptidase-4) with IC50 of 19 nM in Caco-2 cell extracts.