KU0060648 (KU-0060648) is a novel, potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK) with anticancer activity.

KU0060648 HCl is a novel, potent and dual inhibitor of DNA-dependent protein kinase (DNA-PK) and PI3Kα/β/δ (Phosphoinositide 3-kinases) with potential antitumor activity.

PP-121 is a novel, potent and selective multi-targeted RTK (receptor tyrosine kinases) inhibitor with potential antitumor activity.

YU238259 (YU-238259) Is a novel and potent HDR (Homology-Dependent DNA Repair) inhibitor with anticancer activity.

AZD-7648 (AZD7648) is a novel, potent and selective DNA-PK (DNA-dependent protein kinase) inhibitor with potential anticancer/antitumor activity.

Compound 401 is a potent synthetic inhibitor of DNA-dependent protein kinase (DNA-PK, IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro.

LTURM-34 is a potent and selective DNA-PK inhibitor, attenuating proliferation of a wide range of tumor cell lines in vitro.

PIK-75 is a p110α inhibitor with IC50 of 5.8 nM, which is 200-fold more potent than p110β.

CC-115 hydrochloride (CC115 HCl) is a novel and potent dual inhibitor of DNA-PK (DNA-dependent protein kinase) and mTOR (mammalian target of rapamycin) with IC50s of 13 nM and 21 nM, respectively and with potential antineoplastic activity.

NU7026 is a novel and potent DNA-PK (DNA-dependent protein kinase) with potential antitumor activity.