(R)-FT671 is the R-enantiomer of FT671.

FT671 is a novel, potent, high affinity and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM.

GNE-6776 HCl (GNE6776), the hydrochloride salt of GNE-6776 which is an analog of GNE-6640, is a novel potent and selective inhibitor of USP7 (ubiquitin-specific protease-7) with potential anticancer activity.

GNE-6640, an analog of GNE-6776, is a novel potent and selective inhibitor of USP7 (ubiquitin-specific protease-7).