LY-3475070 (LY3475070; LY 3475070) is a novel, potent, oral and selective CD73 inhibitor (cluster of differentiation 73, IC50 = 28 nM) with potential anticancer activity.

Avacopan (CCX168; CCX-168; Tavneos) is a small-molecule C5aR antagonist that blocks the effects of C5a.

NQ301 is a synthetic 1,4-naphthoquinone derivative that acts as a selective CD45 inhibitor, displaying potent antithrombotic/antiplatelet activity. It exerts its antiplatelet activity by inhibiting collagen-challenged rabbit platelet aggregation with IC50 of 10 mg/mL.

CD38 inhibitor 78c is a novel and potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38, exhibiting cardiac protection effects in an ex vivo model of i/r.