FSK hydrochloride

This product is for research use only, not for human use. We do not sell to patients.

FSK hydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$1003-6 Days
10mg$1603-6 Days

Cat #: V91852 CAS #: 3033987-42-4 Purity ≥ 99%

Description: FSK hydrochloride is a fluorosulfonyloxybenzoyl-l-lysine with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride modified nanomolecules can target epidermal growth factor receptor (EGFR) to produce irreversible covalent binding. FSK hydrochloride can capture unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues other than Cys and cross-linking at the binding periphery. FSK hydrochloride can be used to construct a bio-reactive SuFEx system for creating covalent bonds in different proteins in vitro and in vivo.

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Molecular Weight (MW)384.81
Molecular FormulaC13H18ClFN2O6S
CAS No.3033987-42-4
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month


nNote: (1). Please store this product in a sealed and protected environment, avoid exposure to moisture.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5987 mL12.9934 mL25.9869 mL51.9737 mL
5mM0.5197 mL2.5987 mL5.1974 mL10.3947 mL
10mM0.2599 mL1.2993 mL2.5987 mL5.1974 mL
20mM0.1299 mL0.6497 mL1.2993 mL2.5987 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.