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| Size | Price | Stock |
|---|---|---|
| 250mg | $3380 | To Be Confirmed |
| 500mg | $4500 | To Be Confirmed |
: Cat #: V70181 CAS #: 2387898-69-1 Purity ≥ 99%
Description: PBT434 methanesulfonate is a potent, orally bioactive, α-synuclein aggregation inhibitor that crosses the BBB (blood-brain barrier). PBT434 methanesulfonate works as an iron chelator and modulates transcellular iron transport. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated alpha-synuclein aggregation. PBT434 methanesulfonate prevents neuron loss in the substantia nigra pars compacta (SNpc). PBT434 methanesulfonate may be utilized in PD/Parkinson's disease research.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 398.262180089951 |
|---|---|
| Molecular Formula | C13H17Cl2N3O5S |
| CAS No. | 2387898-69-1 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | PBT434 MESYLATE; PBT434 (methanesulfonate); 2387898-69-1; ATH434 MESYLATE; ATH-434 MESYLATE; ATH434; ATH-434; ATH 434; PBT-434 MESYLATE; 826P1VAG3U; EX-A8324; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5109 mL | 12.5545 mL | 25.1091 mL | 50.2182 mL |
| 5mM | 0.5022 mL | 2.5109 mL | 5.0218 mL | 10.0436 mL |
| 10mM | 0.2511 mL | 1.2555 mL | 2.5109 mL | 5.0218 mL |
| 20mM | 0.1255 mL | 0.6277 mL | 1.2555 mL | 2.5109 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.