Prednisone

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$250	Check With Us
50g	$650	Check With Us
100g	$975	Check With Us

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Cat #: V1699 CAS #: 53-03-2 Purity ≥ 98%

Description: Prednisone (also known as Dehydrocortisone; trade names: Adasone; Deltasone, Liquid Pred, Orasone, among others) is an approved glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases.

References: [2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7(4):868-72.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	358.43
Molecular Formula	C21H26O5
CAS No.	53-03-2
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 71 mg/mL (198.1 mM)r
	Water:<1 mg/mLr
	Ethanol: <1 mg/mL
Synonyms	Prednisone; Dehydrocortisone; Deltasone; Meticorten; Decortin; Prednisonum; Deltasone; Encorton; Encortone; Enkortolon

Protocol	In Vivo	Prednisone (intramuscular injection, 10 mg/kg once a day, on days 4 to 13) reduces the survival rate on days lower than the control group in BALB/c mice with encephalomyocarditis virus myocarditis. Besides, myocardial virus titers reaches a maximum on day 4, but there is no antibody titer, and on day 8 virus titers remains elevated and antibody titers is also high. On day 10, antibody titers are significantly lower than controls, while viral titers remains significantly elevated

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.7899 mL	13.9497 mL	27.8995 mL	55.7989 mL
5mM	0.5580 mL	2.7899 mL	5.5799 mL	11.1598 mL
10mM	0.2790 mL	1.3950 mL	2.7899 mL	5.5799 mL
20mM	0.1395 mL	0.6975 mL	1.3950 mL	2.7899 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.