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Prasugrel Hydrochloride (PCR 4099; CS-747)

This product is for research use only, not for human use. We do not sell to patients.

Prasugrel Hydrochloride (PCR 4099; CS-747)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$400Check With Us
1g$650Check With Us
5g$2000Check With Us
email: [email protected]        [email protected]

Cat #: V6224 CAS #: 389574-19-0 Purity ≥ 98%

Description: Prasugrel Hydrochloride (formerly also known as CS-747, PCR 4099 and LY640315), a piperazine derivative, is a novel and potent thienopyridine ADP receptor (P2Y12) antagonist used for the reduction of thrombotic cardiovascular events.

References: Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5(7):1545-51.

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Molecular Weight (MW)409.9004
Molecular FormulaC20H21ClFNO3S
CAS No.389574-19-0
SMILES CodeFC1=CC=CC=C1C(N2CCC3=C(C=C(OC(C)=O)S3)C2)C(C4CC4)=O.[H]Cl
SynonymsPrasugrel Hydrochloride; Prasugrel HCl; CS-747; CS747; CS 747; PCR-4099; PCR4099; PCR 4099; LY-640315; LY640315; LY 640315;
ProtocolIn VivoIn rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4396 mL12.1981 mL24.3962 mL48.7923 mL
5mM0.4879 mL2.4396 mL4.8792 mL9.7585 mL
10mM0.2440 mL1.2198 mL2.4396 mL4.8792 mL
20mM0.1220 mL0.6099 mL1.2198 mL2.4396 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.