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Plecanatide acetate

This product is for research use only, not for human use. We do not sell to patients.

Plecanatide acetate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$450To Be Confirmed
10mg$750To Be Confirmed
25mg$1350To Be Confirmed
50mg$2150To Be Confirmed
email: [email protected]        [email protected]

Cat #: V33986 CAS #: 1075732-84-1 Purity ≥ 95%

Description: Plecanatide acetate, the acetate salt of plecanatide, is a guanylate cyclase-C (GC-C) receptor agonist with anti-inflammatory activity. It activates GCC with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis. Plecanatide (Trulance; SP304; SP-304) is a drug approved by FDA for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation.

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CAS No.1075732-84-1
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.