PKCß inhibitor

This product is for research use only, not for human use. We do not sell to patients.

PKCß inhibitor
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1950Check With Us
1g$2925Check With Us

Cat #: V27043 CAS #: 257879-35-9 Purity ≥ 99%

Description: PKCß inhibitor, an anilino-monoindolylmaleimide compound, is a novel, potent, ATP-competitive and selective inhibitor of PKCß isozymes.

References: Tanaka M, et al. Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5171-4.

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Molecular Weight (MW)411.46
Molecular FormulaC24H21N5O2
CAS No.257879-35-9
SMILES CodeO=C(C(C1=CN(CCCN2C=CN=C2)C3=C1C=CC=C3)=C4NC5=CC=CC=C5)NC4=O
SynonymsPKCß inhibitor
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4304 mL12.1518 mL24.3037 mL48.6074 mL
5mM0.4861 mL2.4304 mL4.8607 mL9.7215 mL
10mM0.2430 mL1.2152 mL2.4304 mL4.8607 mL
20mM0.1215 mL0.6076 mL1.2152 mL2.4304 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.