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Piracetam (UCB-6215)

This product is for research use only, not for human use. We do not sell to patients.

Piracetam (UCB-6215)
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Cat #: V1094 CAS #: 7491-74-9 Purity ≥ 98%

Description: Piracetam (BRN-1526393; UCB-6215; Cl-871; Breinox; Ciclofalina; Euvifor; Gabacet; Nootron) is a cyclized derivative of the neurotransmitter gamma-aminobutyric acid (GABA) that has been approved for use in the treatment of a wide range of cognitive disorders.

References: Mingeot-Leclercq, M.P., et al., Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment. Biochim Biophys Acta, 2003. 1609(1): p. 28-38.

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Molecular Weight (MW)142.16
Molecular FormulaC6H10N2O2
CAS No.7491-74-9
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 72 mg/mL (506.5 mM)rr
Water: 72 mg/mL (506.5 mM)rr
Ethanol: <1 mg/mL
SMILES CodeO=C1N(NC(C)=O)CCC1
SynonymsUCB-6215; Piracetam; Breinox; BRN-1526393; UCB6215; UCB 6215; BRN1526393; Ciclofalina; Cl871; BRN 1526393; Cl-871; Cl 871; EINECS 231-312-7; Euvifor; Gabacet; Genogris; Nootron; Nootropil; Nootropyl; Normabrain.
ProtocolIn VitroPiracetam (UCB-6215) is able to significantly decrease the fusogenic and destabilising effect of Abeta 29-42, in a concentration-dependent manner. Preincubation of piracetam, at a piracetam/peptide ratio of 960, during 20 min before the addition of Abeta 29-42 prevents almost completely the mixture of the two fluorescent probes. Preincubation of piracetam with lipids prevents almost completely the release of calcein induced by the peptide in a dose-dependent fashion (piracetam/peptide ratios from 9.6 to 960)
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM7.0343 mL35.1716 mL70.3433 mL140.6866 mL
5mM1.4069 mL7.0343 mL14.0687 mL28.1373 mL
10mM0.7034 mL3.5172 mL7.0343 mL14.0687 mL
20mM0.3517 mL1.7586 mL3.5172 mL7.0343 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.