Piperaquine tetraphosphate tetrahydrate

This product is for research use only, not for human use. We do not sell to patients.

Piperaquine tetraphosphate tetrahydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$1403-6 Days
50mg$2303-6 Days
100mg$3303-6 Days
250mg$5803-6 Days
500mg$8503-6 Days
1g$12303-6 Days

Cat #: V28794 CAS #: 915967-82-7 Purity ≥ 99%

Description: Piperaquine tetraphosphate tetrahydrate, a bisquinoline analog, is a potent antiparasitic agent that has been widely used in combination with other antimalarial agents such as dihydroartemisinin to treat malaria. Piperaquine was developed under the Chinese National Malaria Elimination Programme in the 1960s and was adopted throughout China as a replacement for the structurually similar antimalarial drug chloroquine. Due to widespread parasite resistance to piperaquine, the drug fell out of use as a monotherapy, and is instead used as a partner drug for artemisinin combination therapy. Piperaquine kills parasites by disrupting the detoxification of host heme.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)999.552430152893
Molecular FormulaC29H52CL2N6O20P4
CAS No.915967-82-7
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsPiperaquine phosphate hydrate; Piperaquine phosphate; Piperaquine tetraphosphate hydrate
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.0004 mL5.0022 mL10.0045 mL20.0090 mL
5mM0.2001 mL1.0004 mL2.0009 mL4.0018 mL
10mM0.1000 mL0.5002 mL1.0004 mL2.0009 mL
20mM0.0500 mL0.2501 mL0.5002 mL1.0004 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.