Picolinamide
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $200 | Check With Us |
| 100g | $600 | Check With Us |
| 200mg | $900 | Check With Us |
: Cat #: V2572 CAS #: 1452-77-3 Purity ≥ 98%
Description: Picolinamide (2-Pyridinecarboxamide, Picolinoylamide, 2-Carbamoylpyridine) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 122.12 |
|---|---|
| Molecular Formula | C6H6N2O |
| CAS No. | 1452-77-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 24 mg/mL (196.5 mM)r |
| Water: 24 mg/mL (196.5 mM)r | |
| Ethanol: 24 mg/mL (196.5 mM) | |
| Synonyms | 2-Pyridinecarboxamide, Picolinoylamide, 2-Carbamoylpyridine |
| Protocol | In Vivo | Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles |
|---|---|---|
| Animal model | Rats | |
| Dosages | 4 mmol/kg | |
| Administration | Intraperitoneal injection (i.p.) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 8.1887 mL | 40.9433 mL | 81.8867 mL | 163.7733 mL |
| 5mM | 1.6377 mL | 8.1887 mL | 16.3773 mL | 32.7547 mL |
| 10mM | 0.8189 mL | 4.0943 mL | 8.1887 mL | 16.3773 mL |
| 20mM | 0.4094 mL | 2.0472 mL | 4.0943 mL | 8.1887 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.