PHTPP

This product is for research use only, not for human use. We do not sell to patients.

PHTPP
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$2103-6 Days
50mg$3303-6 Days
100mg$4603-6 Days
250mg$6803-6 Days
500mg$9503-6 Days

Cat #: V3204 CAS #: 805239-56-9 Purity ≥ 99%

Description: PHTPP is an estrogen receptor (ERβ) antagonist. It exhibits 36-fold selectivity for ERβ relative to ERα. PHTPP has no effect on basal cAMP production but reduces FSH-mediated cAMP production by 80%. PHTPP does not suppress E2-stimulated ERα activity, but it does inhibit E2-stimulated ERβ activity (at a concentration of 10-6 M). When taken in large quantities, PHTPP both promotes and modestly elevates the expression of class 1 Igf1 mRNA in response to DPN.

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Promise
Molecular Weight (MW)423.31
Molecular FormulaC20H11F6N3O
CAS No.805239-56-9
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsPHTPP
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3623 mL11.8117 mL23.6233 mL47.2467 mL
5mM0.4725 mL2.3623 mL4.7247 mL9.4493 mL
10mM0.2362 mL1.1812 mL2.3623 mL4.7247 mL
20mM0.1181 mL0.5906 mL1.1812 mL2.3623 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.