Phosphoramidon disodium salt
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1450 | To Be Confirmed |
| 500mg | $2250 | To Be Confirmed |
| 1g | $3375 | To Be Confirmed |
: Cat #: V1913 CAS #: 164204-38-0 Purity ≥ 98%
Description: Phosphoramidon disodium salt is a potent metalloendopeptidase inhibitor, which is widely used as a biochemical research tool.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 588.48 |
|---|---|
| Molecular Formula | C23H34N3Na2O10P |
| CAS No. | 164204-38-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (169.9 mM)r |
| Water: 100 mg/mL (169.9 mM)r | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O[C@H]1[C@H](C)O[C@@H](OP(N[C@@H](CC(C)C)C(N[C@H](C(O[Na])=O)CC2=CNC3=CC=CC=C23)=O)(O[Na])=O)[C@H](O)[C@@H]1O |
| Synonyms | Phosphoramidon sodium |
| Protocol | In Vitro | Phosphoramidon (1-500 μM; 30 min) inhibits ET-converting enzyme (ECE) activity in a dose-dependent manner in solubilized rabbit lung membranes. |
|---|---|---|
| In Vivo | Phosphoramidon (0.25 mg/kg per min; i.v.) suppresses the hypertensive effect of big endothelin-1 in rats. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6993 mL | 8.4965 mL | 16.9929 mL | 33.9859 mL |
| 5mM | 0.3399 mL | 1.6993 mL | 3.3986 mL | 6.7972 mL |
| 10mM | 0.1699 mL | 0.8496 mL | 1.6993 mL | 3.3986 mL |
| 20mM | 0.0850 mL | 0.4248 mL | 0.8496 mL | 1.6993 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.