Phillygenin

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$650	To Be Confirmed
500mg	$1150	To Be Confirmed
1g	$1725	To Be Confirmed

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Cat #: V30439 CAS #: 487-39-8 Purity ≥ 99%

Description: Phillygenin (Phillygenol, Phillygenol; Epipinoresinol methyl ether, Sylvatesmin, Forsythigenol) is a naturally occurringa bioactive intergradient isolated from Osmanthus fragrans, showing diverse bioactivities such as anti-inflammatory, anti-obesity and antipyretic activities.

References: Ye LH et al. Determination of phillygenin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Eur J Drug Metab Pharmacokinet, 2013 Sep, 38(3):201-7.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	372.41
Molecular Formula	C21H24O6
CAS No.	487-39-8
SMILES Code	NC1=NC(C2=CC=CC(OC)=C2)=CC(NCC3=CC=C(OCO4)C4=C3)=N1.[H]Cl
Synonyms	AMBMP HCl; AMBMP Hydrochloride; BML284 HCl; Wnt Agonist; BML284 HCl; BML-284 HCl; BML 284 HCl;

Protocol	In Vitro	Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.
Protocol	In Vivo	The reference for rat is 5.6 mg/m l ( i.v).

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.6852 mL	13.4261 mL	26.8521 mL	53.7043 mL
5mM	0.5370 mL	2.6852 mL	5.3704 mL	10.7409 mL
10mM	0.2685 mL	1.3426 mL	2.6852 mL	5.3704 mL
20mM	0.1343 mL	0.6713 mL	1.3426 mL	2.6852 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.