Phenyl ethyl ketone

This product is for research use only, not for human use. We do not sell to patients.

Phenyl ethyl ketone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$250To Be Confirmed
25g$300To Be Confirmed
50g$450To Be Confirmed

Cat #: V27489 CAS #: 93-55-0 Purity ≥ 99%

Description: Phenyl ethyl ketone is an aryl ketone which is colorless, sweet-smelling and is used in the preparation of other compounds.

References: Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.

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Molecular Weight (MW)134.18
Molecular FormulaC9H10O
CAS No.93-55-0
ProtocolIn VitroLP-935509 inhibits μ2 phosphorylation with an IC50 value of 2.8 ± 0.4 nM, inhibits phosphorylation of a peptide derived from the μ2 protein with an IC50 value of 3.3 ± 0.7 nM
In VivoLP-935509 (0-60 mg/kg; PO, single) causes a robust reduction in pain behavior
Animal modelMale C57BL/6J mice (with SNL(spinal nerve ligation) injury, n=8-10 male mice per group)
Dosages0, 10, 30 and 60 mg/kg (10 ml/kg)
AdministrationPO, single
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM7.4527 mL37.2634 mL74.5268 mL149.0535 mL
5mM1.4905 mL7.4527 mL14.9054 mL29.8107 mL
10mM0.7453 mL3.7263 mL7.4527 mL14.9054 mL
20mM0.3726 mL1.8632 mL3.7263 mL7.4527 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.