This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 100mg | $2025 | Check With Us |
| 200mg | $3037 | Check With Us |
| 500mg | $5125 | Check With Us |
: Cat #: V4482 CAS #: 1004990-28-6 Purity ≥ 98%
Description: PF-AKT400 (AKT-0286; ZINC-111606147), designed based on a 3-aminopyrrolidine scaffold, is a novel, selective, potent, ATP-competitive Akt kinase inhibitor with antitumor activity.
References: Chen SF, et al. Binding selectivity studies of PKBα using molecular dynamics simulation and free energy calculations. J Mol Model. 2013 Nov;19(11):5097-5112.
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| Molecular Weight (MW) | 400.43 |
|---|---|
| Molecular Formula | C20H22F2N6O |
| CAS No. | 1004990-28-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(NC[C@]1(N)CN(C2=C3C(NC=C3CC)=NC=N2)CC1)C4=CC=C(F)C=C4F |
| Synonyms | PFAKT400; AKT protein kinase inhibitor; PF AKT400; PF-AKT400; AKT0286; ZINC-111606147; Lig-1; Lig 1; PF AKT400; AKT-0286; AKT 0286; ZINC 111606147; ZINC111606147; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4973 mL | 12.4866 mL | 24.9732 mL | 49.9463 mL |
| 5mM | 0.4995 mL | 2.4973 mL | 4.9946 mL | 9.9893 mL |
| 10mM | 0.2497 mL | 1.2487 mL | 2.4973 mL | 4.9946 mL |
| 20mM | 0.1249 mL | 0.6243 mL | 1.2487 mL | 2.4973 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.