PF-1022A

This product is for research use only, not for human use. We do not sell to patients.

PF-1022A
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2100To Be Confirmed
250mg$3400To Be Confirmed
1g$5100To Be Confirmed

Cat #: V4481 CAS #: 133413-70-4 Purity ≥ 98%

Description: PF-1022A (PF1022A) is a novel and potent N-methylated cyclooctadepsipeptides (CODPs) with excellent anthelmintic properties and acts as an ionophore.

References: Dornetshuber R, et al. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44.

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Product Promise

Promise
Molecular Weight (MW)949.18
Molecular FormulaC₅₂H₇₆N₄O₁₂
CAS No.133413-70-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C([C@H](CC(C)C)N(C)C([C@@H](CC1=CC=CC=C1)OC([C@H](CC(C)C)N(C)C([C@@H](C)OC([C@H](CC(C)C)N(C)C([C@@H](CC2=CC=CC=C2)OC([C@H](CC(C)C)N3C)=O)=O)=O)=O)=O)=O)O[C@H](C)C3=O
SynonymsPF 1022A; PF1022A; PF-1022A
ProtocolIn VitroPF 1022A binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes. Furthermore, PF 1022A binds to GABA receptors, which might contribute to the anthelmintic effect.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.0535 mL5.2677 mL10.5354 mL21.0708 mL
5mM0.2107 mL1.0535 mL2.1071 mL4.2142 mL
10mM0.1054 mL0.5268 mL1.0535 mL2.1071 mL
20mM0.0527 mL0.2634 mL0.5268 mL1.0535 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.