PF-06424439 Mesylate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $600 | To Be Confirmed |
| 250mg | $1250 | To Be Confirmed |
| 500mg | $1875 | To Be Confirmed |
: Cat #: V27355 CAS #: 1469284-79-4 Purity ≥ 99%
Description: PF-06424439 Mesylate, the mesylate salt of PF06424439, is a novel and potent inhibitor of diacylglycerol acyltransferase 2 (DGAT2, IC50 = 14 nM) with lipid lowering effects.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 536.048 |
|---|---|
| Molecular Formula | C23H30ClN7O4S |
| CAS No. | 1469284-79-4 |
| SMILES Code | O=C([C@H]1CN(C2=CC=C3C(NC(C4(N5N=CC(Cl)=C5)CC4)=N3)=N2)CCC1)N6CCCC6.CS(=O)(O)=O |
| Synonyms | PF-06424439 Mesylate; PF 06424439 Mesylate; PF06424439 Mesylate; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8655 mL | 9.3275 mL | 18.6550 mL | 37.3101 mL |
| 5mM | 0.3731 mL | 1.8655 mL | 3.7310 mL | 7.4620 mL |
| 10mM | 0.1866 mL | 0.9328 mL | 1.8655 mL | 3.7310 mL |
| 20mM | 0.0933 mL | 0.4664 mL | 0.9328 mL | 1.8655 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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V1
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C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.