PF-00835231 (PF-835231)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1200 | Check With Us |
200mg | $1800 | Check With Us |
500mg | $3035 | Check With Us |
Cat #: V41524 CAS #: 870153-29-0 Purity ≥ 99%
Description: PF-00835231 (PF-835231) is a potent 3CLpro [main protease (Mpro)] inhibitor developed by Pfizer for COVID-19 treatment.
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Molecular Weight (MW) | 472.53 |
---|---|
Molecular Formula | C24H32N4O6 |
CAS No. | 870153-29-0 |
SMILES Code | OCC([C@H](C[C@@H]1CCNC1=O)NC([C@H](CC(C)C)NC(C2=CC3=C(OC)C=CC=C3N2)=O)=O)=O |
Synonyms | PF 835231; PF-835231; PF835231; PF 00835231; PF-00835231; PF00835231 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.1163 mL | 10.5813 mL | 21.1627 mL | 42.3254 mL |
5mM | 0.4233 mL | 2.1163 mL | 4.2325 mL | 8.4651 mL |
10mM | 0.2116 mL | 1.0581 mL | 2.1163 mL | 4.2325 mL |
20mM | 0.1058 mL | 0.5291 mL | 1.0581 mL | 2.1163 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.