Perindopril Erbumine (S-9490-3)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$445	Check With Us
5g	$745	Check With Us
10g	$1115	Check With Us

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Cat #: V1782 CAS #: 107133-36-8 Purity ≥ 98%

Description: Perindopril Erbumine (also called S9490-3; Pirindopril; ACEON; Perindopril tert-butylamine; Perstarium), the tert-butylamine salt of perindopril, is a long acting and brain penetrant ACE (angiotensin-converting enzyme) inhibitor with anti-hypertensive effects.

References: Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	441.6
Molecular Formula	C19H32N2O5.C4H11N
CAS No.	107133-36-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: <1 mg/mLr
	Water: 88 mg/mL (199.3 mM)r
	Ethanol: 88 mg/mL (199.3 mM)
Solubility In Vivo	Saline: 30 mg/mL
Synonyms	S 9490; S-9490; Pirindopril; S9490; S 9490-3; S9490-3; ACEON; Perindopril tert-butylamine; Perstarium; S 9490 3; S 94903.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2645 mL	11.3225 mL	22.6449 mL	45.2899 mL
5mM	0.4529 mL	2.2645 mL	4.5290 mL	9.0580 mL
10mM	0.2264 mL	1.1322 mL	2.2645 mL	4.5290 mL
20mM	0.1132 mL	0.5661 mL	1.1322 mL	2.2645 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.