Penicillin G sodium

This product is for research use only, not for human use. We do not sell to patients.

Penicillin G sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$645Check With Us
10g$1100Check With Us
20g$1650Check With Us

Cat #: V5329 CAS #: 69-57-8 Purity ≥ 98%

Description: Penicillin G sodium, the sodium salt of penicillin G, is a typical penicillin derivative and β-lactam antibiotic commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections.

References: Yang J, et al. Spectroscopic analysis and docking simulation on the recognition and binding of TEM-1 β-lactamase with β-lactam antibiotics. Exp Ther Med. 2017 Oct;14(4):3288-3298.

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Molecular Weight (MW)356.37
Molecular FormulaC16H17N2NaO4S
CAS No.69-57-8
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
SMILES CodeO=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(CC3=CC=CC=C3)=O)N1C2=O)[O-].[Na+]
SynonymsNSC 402815; OK 431; Pen-A-Brasive; Penicillin G sodium; Monosodium benzylpenicillin; Mycofarm; Novocillin;
ProtocolIn VitroThe Ultraviolet-visible (UV-Vis) absorption spectrum of the Penicillin G sodium salt-TEM-1 system is markedly different to that of Penicillin G sodium salt and TEM-1 β-lactamase, indicating the formation of new complexes between Penicillin G sodium salt and TEM-1 β-lactamase.
In VivoIn the logistic regression model, the probability of a positive swab in the control group is 1.6 times higher than that in the pigs treated with Penicillin G sodium salt (P<0.05). In the control group, the risk of a swab having 10 to 99 colonies per plate, compare to having zero per plate, is 2.3 times greater than that in the pigs treated with Penicillin G sodium salt (P=0.022).
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8061 mL14.0304 mL28.0607 mL56.1214 mL
5mM0.5612 mL2.8061 mL5.6121 mL11.2243 mL
10mM0.2806 mL1.4030 mL2.8061 mL5.6121 mL
20mM0.1403 mL0.7015 mL1.4030 mL2.8061 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.