Pemirolast potassium (TWT-8152; BMY 26517)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$600	Check With Us
5g	$1090	Check With Us
10g	$1635	Check With Us

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Cat #: V1241 CAS #: 100299-08-9 Purity ≥ 98%

Description: Pemirolast potassium (formerly TWT 8152; BMY 26517; TWT-8152; BMY-26517; Alegysal and Alamast), the potassium salt of Pemirolast, is a poten and orally bioactive histamine H1 antagonist and mast cell stabilizer with potential antiallergic effects.

References: Kemp, J.P., et al., Pemirolast, a new oral nonbronchodilator drug for chronic asthma. Ann Allergy, 1992. 68(6): p. 488-91.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	266.3
Molecular Formula	C10H7N6O.K
CAS No.	100299-08-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: <1 mg/mLr
	Water: 53 mg/mL (199.0 mM)r
	Ethanol: <1 mg/mL
Synonyms	TWT-8152; BMY 26517; TWT 8152; BMY 26517; TWT8152; BMY 26517; Pemirolast; Pemirolast potassium. trade name: Alegysal and Alamast.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.7552 mL	18.7758 mL	37.5516 mL	75.1033 mL
5mM	0.7510 mL	3.7552 mL	7.5103 mL	15.0207 mL
10mM	0.3755 mL	1.8776 mL	3.7552 mL	7.5103 mL
20mM	0.1878 mL	0.9388 mL	1.8776 mL	3.7552 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.