PD 151746

This product is for research use only, not for human use. We do not sell to patients.

PD 151746
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1250Check With Us
1g$1875Check With Us

Cat #: V0704 CAS #: 179461-52-0 Purity ≥ 98%

Description: PD 151746 (PD-151746) is a novel, potent, selective, and cell-permeable calpain inhibitor with important biological activity.

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Molecular Weight (MW)237.25
Molecular FormulaC11H8FNO2S
CAS No.179461-52-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 47 mg/mL (198.1 mM)r
Water: <1 mg/mLr
Ethanol: 47 mg/mL (198.1 mM)
SMILES CodeO=C(O)/C(S)=C/C1=CNC2=C1C=C(F)C=C2
SynonymsPD 151746; PD151746; PD-151746;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2150 mL21.0748 mL42.1496 mL84.2993 mL
5mM0.8430 mL4.2150 mL8.4299 mL16.8599 mL
10mM0.4215 mL2.1075 mL4.2150 mL8.4299 mL
20mM0.2107 mL1.0537 mL2.1075 mL4.2150 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.