Oxybutynin chloride

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$260	Check With Us
5g	$500	Check With Us
10g	$750	Check With Us

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Cat #: V1193 CAS #: 1508-65-2 Purity ≥ 98%

Description: Oxybutynin chloride (Ditropan; Ditropan XL), the hydrochloride salt of oxybutynin, is a competitive antagonist of muscarinic acetylcholine receptor subtypes M1, M2, and M3 used to treat bladder and urinary conditions (i.e. overactive bladder, urinary and bladder difficulties).

References: Li H, et al. The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	393.95
Molecular Formula	C22H31NO3.HCl
CAS No.	1508-65-2
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 79 mg/mL (200.5 mM)rr
	Water: 4 mg/mL (10.15 mM)rr
	Ethanol: 79 mg/mL (200.5 mM)
SMILES Code	O=C(OCC#CCN(CC)CC)C(O)(C1CCCCC1)C2=CC=CC=C2.[H]Cl
Synonyms	Oxybutynin hydrochloride; Oxybutynin HCl

Protocol	In Vitro	Oxybutynin chloride (0.1, 0.3, 1, 3, 10, 30, 100 μM; 200 ms) inhibits vascular Kv channels in a concentration-dependent manner independent of anticholinergic effect in coronary arterial smooth muscle cells

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5384 mL	12.6920 mL	25.3839 mL	50.7679 mL
5mM	0.5077 mL	2.5384 mL	5.0768 mL	10.1536 mL
10mM	0.2538 mL	1.2692 mL	2.5384 mL	5.0768 mL
20mM	0.1269 mL	0.6346 mL	1.2692 mL	2.5384 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.