Otilonium Bromide (Octylonium bromide; SP63)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$480	Check With Us
1g	$800	Check With Us
5g	$2400	Check With Us

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Cat #: V1192 CAS #: 26095-59-0 Purity ≥ 98%

Description: Otilonium bromide (SP-63; Octylonium bromide; SP63; trade name Spasmomen among others) is a potent anti-muscarinic agent and a CCB (calcium channel blocker) used to relieve spasmodic pain of the gut, in particular in irritable bowel syndrome.

References: Battaglia, G., et al., Otilonium bromide in irritable bowel syndrome: a double-blind, placebo-controlled, 15-week study. Aliment Pharmacol Ther, 1998. 12(10): p. 1003-10.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	563.57
Molecular Formula	C29H43BrN2O4
CAS No.	26095-59-0
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 113 mg/mL (200.5 mM)rr
	Water: 113 mg/mL (200.5 mM)rr
	Ethanol: 113 mg/mL (200.5 mM)
SMILES Code	O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-]
Synonyms	SP-63; Octylonium bromide; SP 63; SP63;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.7744 mL	8.8720 mL	17.7440 mL	35.4880 mL
5mM	0.3549 mL	1.7744 mL	3.5488 mL	7.0976 mL
10mM	0.1774 mL	0.8872 mL	1.7744 mL	3.5488 mL
20mM	0.0887 mL	0.4436 mL	0.8872 mL	1.7744 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.