Oritavancin diphosphate (LY333328)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$1450	In Stock
500mg	$2300	In Stock
1g	$3450	In Stock

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Cat #: V4904 CAS #: 192564-14-0 Purity ≥ 98%

Description: Oritavancin diphosphate (LY-333328; LY 333328; LY333328; trade name Orbactiv), the diphosphate of Oritavancin, is a semisynthetic lipoglycopeptide analog of vancomycin approved in 2014 by FDA as an antibiotic for the treatment of serious Gram-positive bacterial infections.

References: Arhin FF, et al. Effect of polysorbate 80 on oritavancin binding to plastic surfaces: implications for susceptibility testing. Antimicrob Agents Chemother. 2008 May;52(5):1597-1603.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	1989.09
Molecular Formula	C86H103Cl3N10O34P2
CAS No.	192564-14-0
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	C[C@H]1[C@H](O)[C@@](C)(N)C[C@H](O[C@H]2[C@H]3C(N[C@H](C(O)=O)C4=CC(O)=CC(O)=C4C5=C(O)C=CC([C@@H](NC([C@H]6C7=CC(OC8=C(Cl)C=C2C=C8)=C(O[C@H]9[C@H](O[C@H]%10C[C@](C)(NCC%11=CC=C(C%12=CC=C(Cl)C=C%12)C=C%11)[C@@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9)C(OC%13=C(Cl)C=C([C@@H](O)[C@@H](NC([C@H](NC)CC(C)C)=O)C(N[C@@H](CC(N)=O)C(N6)=O)=O)C=C%13)=C7)=O)C(N3)=O)=C5)=O)O1.O=P(O)(O)O.O=P(O)(O)O
Synonyms	LY333328; Oritavancin; Oritavancin diphosphate; LY-333328; LY 333328

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.5027 mL	2.5137 mL	5.0274 mL	10.0548 mL
5mM	0.1005 mL	0.5027 mL	1.0055 mL	2.0110 mL
10mM	0.0503 mL	0.2514 mL	0.5027 mL	1.0055 mL
20mM	0.0251 mL	0.1257 mL	0.2514 mL	0.5027 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.