Olaparib D5

This product is for research use only, not for human use. We do not sell to patients.

Olaparib D5
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$2503-6 Days
5mg$6203-6 Days
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V40441 CAS #: 2143107-56-4 Purity ≥ 99%

Description: Olaparib D5 is a penta-deuterated form of Olaparib ( AZD2281; KU59436; KU-0059436; Lynparza) which is an orally bioavailable PARP inhibitor approved as an anticancer medication.

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Molecular Weight (MW)439.49
Molecular FormulaC24H23FN4O3
CAS No.2143107-56-4
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2754 mL11.3768 mL22.7536 mL45.5073 mL
5mM0.4551 mL2.2754 mL4.5507 mL9.1015 mL
10mM0.2275 mL1.1377 mL2.2754 mL4.5507 mL
20mM0.1138 mL0.5688 mL1.1377 mL2.2754 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.