NUCC-390 diHCl

This product is for research use only, not for human use. We do not sell to patients.

NUCC-390 diHCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$1450To Be Confirmed
100mg$2450To Be Confirmed
200mg$3675To Be Confirmed

Cat #: V38879 Purity ≥ 99%

Description: NUCC-390 diHCl is a novel, potent, and specific small-molecule CXCR4 receptor agonist.

References: Mishra RK, et al. Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists.Sci Rep. 2016 Jul 26;6:30155.

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Product Promise

Promise
Molecular Weight (MW)468.46
Molecular FormulaC₂₃H₃₅Cl₂N₅O
SMILES CodeO=C(N1CCCCC1)C2=NN(CCC)C3=C2CC(NCCC4=CC=NC=C4)CC3.Cl.Cl
ProtocolIn VitroNUCC-390 dihydrochloride (10 μM) produces strong (Ca)i response, but this effect can be blocked by the known potent and selective CXCR4 antagonist AMD3100
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1347 mL10.6733 mL21.3465 mL42.6931 mL
5mM0.4269 mL2.1347 mL4.2693 mL8.5386 mL
10mM0.2135 mL1.0673 mL2.1347 mL4.2693 mL
20mM0.1067 mL0.5337 mL1.0673 mL2.1347 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.