NSC19005

This product is for research use only, not for human use. We do not sell to patients.

NSC19005
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Size Price Stock
500mg$1850Check With Us
1g$2750Check With Us
5g$7450Check With Us

Cat #: V26713 CAS #: 5452-87-9 Purity ≥ 99%

Description: NSC19005 (Betahistine EP Impurity C) is an impurity of Betahistine and is structurally related to Betahistine.

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Molecular Weight (MW)241.33
Molecular FormulaC15H19N3
CAS No.5452-87-9
ProtocolIn VitroBetahistine (0-10 μM) inhibits [125I]iodoproxyfan binding to membranes of CHO (rH3(445)R) and CHO (hH3(445)R) cells with IC50 values of 1.9 μM and 3.3 μM, respectively. Lead to Ki values of 1.4 μM and 2.5 μM, respectively
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.1437 mL20.7185 mL41.4370 mL82.8741 mL
5mM0.8287 mL4.1437 mL8.2874 mL16.5748 mL
10mM0.4144 mL2.0719 mL4.1437 mL8.2874 mL
20mM0.2072 mL1.0359 mL2.0719 mL4.1437 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.