NSC-60339
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2650 | Check With Us |
| 250mg | $4200 | Check With Us |
| 500mg | $6300 | Check With Us |
: Cat #: V26730 CAS #: 70-09-7 Purity ≥ 99%
Description: NSC-60339 is an antibiotic.
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| Molecular Weight (MW) | 486.95 |
|---|---|
| Molecular Formula | C26H23ClN6O2 |
| CAS No. | 70-09-7 |
| SMILES Code | O=C(NC1=CC=C(C2=NCCN2)C=C1)C3=CC=C(C(NC4=CC=C(C5=NCCN5)C=C4)=O)C=C3Cl |
| Synonyms | Phthalanilide; Wander; NSC-60339; NSC 60339; NSC60339; |
| Protocol | In Vitro | NSC 60339 has been correlated with the sensitivity, resistance, or cross-resistance of 7 tumor lines to phthalanilide treatment in vivo. The sensitive tumors (L1210, L1210/MTX, L1210/ara-C, and P815) rapidly takes up the drug and retained it primarily as lipid-bound drug for the 24-hr experimental period. The resistant tumor, L1210/NSC 60339, and 2 cross-resistant tumors, P388/VCR and P815/VLB, took up as much drug as the sensitive tumors did by 0.5 hr, but there was an efflux of lipid-bound drug from these resistant tumors by 24 hr. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0536 mL | 10.2680 mL | 20.5360 mL | 41.0720 mL |
| 5mM | 0.4107 mL | 2.0536 mL | 4.1072 mL | 8.2144 mL |
| 10mM | 0.2054 mL | 1.0268 mL | 2.0536 mL | 4.1072 mL |
| 20mM | 0.1027 mL | 0.5134 mL | 1.0268 mL | 2.0536 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.