NSC-40738
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $290 | Check With Us |
| 2g | $500 | Check With Us |
| 5g | $840 | Check With Us |
: Cat #: V19623 CAS #: 67-47-0 Purity ≥ 99%
Description: NSC-40738 is a novel and potent biochemical for treatment of sickle cell anemia.
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- Related Biological Data
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| Molecular Weight (MW) | 126.11 |
|---|---|
| Molecular Formula | C6H6O3 |
| CAS No. | 67-47-0 |
| SMILES Code | O=CC1=CC=C(CO)O1 |
| Synonyms | AES 103;5-HMF-AesRx; 5-hydroxymethyl furfural; NSC-40738; BAX-555; 5-HMF; AES-103; NSC40738; BAX555; 5HMF; AES103; NSC 40738; BAX 555; 5 HMF; |
| Protocol | In Vitro | It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 7.9296 mL | 39.6479 mL | 79.2959 mL | 158.5917 mL |
| 5mM | 1.5859 mL | 7.9296 mL | 15.8592 mL | 31.7183 mL |
| 10mM | 0.7930 mL | 3.9648 mL | 7.9296 mL | 15.8592 mL |
| 20mM | 0.3965 mL | 1.9824 mL | 3.9648 mL | 7.9296 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.