Norethindrone

This product is for research use only, not for human use. We do not sell to patients.

Norethindrone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$400Check With Us
10g$650Check With Us
20g$975Check With Us

Cat #: V26605 CAS #: 68-22-4 Purity ≥ 99%

Description: Norethindrone (Norethisterone; sold under many trade names) is a synthetic progestin used as an orally active contraceptive for birth controls.

References: Muneyyirci-Delale O, et al. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 1998 Jan-Feb;43(1):24-7.

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Molecular Weight (MW)298.42
Molecular FormulaC20H26O2
CAS No.68-22-4
SMILES CodeC[C@]12CC[C@H]3[C@@H](CCC4=CC(CC[C@H]34)=O)[C@@H]1CC[C@@]2(O)C#C
SynonymsNorethindrone, Norethisterone, 19-nor-17α-ethynyltestosterone, Utovlan
ProtocolIn VivoNorethindrone acetate could be a cost-effective alternative with relatively mild side effects in the treatment of symptomatic endometriosis. Subjects treated with norethindrone acetate obtain dysmenorrhea and noncyclic pelvic pain relief.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3510 mL16.7549 mL33.5098 mL67.0196 mL
5mM0.6702 mL3.3510 mL6.7020 mL13.4039 mL
10mM0.3351 mL1.6755 mL3.3510 mL6.7020 mL
20mM0.1675 mL0.8377 mL1.6755 mL3.3510 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.