Nitrendipine (BAY-E-5009)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
500mg | $250 | Check With Us |
1g | $450 | Check With Us |
5g | $1170 | Check With Us |
Cat #: V1274 CAS #: 39562-70-4 Purity ≥ 98%
Description: Nitrendipine (BAY-E5009; BAY E-5009; Bayotensin; Bayotensin, Baypress, Nidrel, Deiten) is a potent dihydropyridine (DHP) calcium channel blocker (CCB) with antihypertensive effects.
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Molecular Weight (MW) | 360.37 |
---|---|
Molecular Formula | C18H20N2O6 |
CAS No. | 39562-70-4 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 72 mg/mL (199.8 mM)r |
Water: <1 mg/mLr | |
Ethanol:<1 mg/mL | |
Solubility In Vivo | IUPAC/Chemical Name: 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate InChi Key: PVHUJELLJLJGLN-UHFFFAOYSA-N InChi Code: InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3 SMILES Code: CCOC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC([N+]([O-])=O)=CC=C2)=O |
Synonyms | BAY-E5009; BAY E-5009; BAY E5009; Bayotensin; Nitrendipine, Bayotensin, Baypress, Nidrel, Deiten |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.7749 mL | 13.8746 mL | 27.7493 mL | 55.4985 mL |
5mM | 0.5550 mL | 2.7749 mL | 5.5499 mL | 11.0997 mL |
10mM | 0.2775 mL | 1.3875 mL | 2.7749 mL | 5.5499 mL |
20mM | 0.1387 mL | 0.6937 mL | 1.3875 mL | 2.7749 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.