Nifedipine D6

This product is for research use only, not for human use. We do not sell to patients.

Nifedipine D6
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$1250To Be Confirmed
25mg$1875To Be Confirmed
50mg$2825To Be Confirmed

Cat #: V33654 CAS #: 1188266-14-9 Purity ≥ 99%

Description: Nifedipine D6 is the hexa-deuterated form of Nifedipine (Bay-1040; Cordipin; BAY-a-1040; Corinfar) which is an approved antihypertensive drug of the dihydropyridine calcium channel blocker (CCB) class.

References: Patel DP, et al. Highly sensitive and rapid ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of nifedipine in human plasma and its application to a bioequivalence study. Biomed Chromatogr. 2012 Dec;26(12):1509-

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Molecular Weight (MW)352.37
Molecular FormulaC₁₇H₁₂D₆N₂O₆
CAS No.1188266-14-9
SynonymsBAY-a-1040 D6
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8379 mL14.1896 mL28.3793 mL56.7585 mL
5mM0.5676 mL2.8379 mL5.6759 mL11.3517 mL
10mM0.2838 mL1.4190 mL2.8379 mL5.6759 mL
20mM0.1419 mL0.7095 mL1.4190 mL2.8379 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.