Neostigmine Bromide (Eustigmin; Neoserine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
5g | $400 | Check With Us |
10g | $650 | Check With Us |
20g | $975 | Check With Us |
Cat #: V1180 CAS #: 114-80-7 Purity ≥ 98%
Description: Neostigmine Bromide (Eustigmin bromide; Neoserine bromide) is a reversible acetylcholinesterase inhibitor and a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage.
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Molecular Weight (MW) | 303.2 |
---|---|
Molecular Formula | C12H19N2O2.Br |
CAS No. | 114-80-7 |
Storage | -20℃ for 3 years in powder formrr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: <1 mg/mLrr |
Water: 60 mg/mL (197.9 mM)rr | |
Ethanol: <1 mg/mL | |
SMILES Code | C[N+](C)(C)C1=CC=CC(OC(N(C)C)=O)=C1.[Br-] |
Synonyms | Eustigmin bromide; Neoserine bromide |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.2982 mL | 16.4908 mL | 32.9815 mL | 65.9631 mL |
5mM | 0.6596 mL | 3.2982 mL | 6.5963 mL | 13.1926 mL |
10mM | 0.3298 mL | 1.6491 mL | 3.2982 mL | 6.5963 mL |
20mM | 0.1649 mL | 0.8245 mL | 1.6491 mL | 3.2982 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.