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Neostigmine Bromide (Eustigmin; Neoserine)

This product is for research use only, not for human use. We do not sell to patients.

Neostigmine Bromide (Eustigmin; Neoserine)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$400Check With Us
10g$650Check With Us
20g$975Check With Us

Cat #: V1180 CAS #: 114-80-7 Purity ≥ 98%

Description: Neostigmine Bromide (Eustigmin bromide; Neoserine bromide) is a reversible acetylcholinesterase inhibitor and a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage.

References: Trevisani, G.T., N.H. Hyman, and J.M. Church, Neostigmine: safe and effective treatment for acute colonic pseudo-obstruction. Dis Colon Rectum, 2000. 43(5): p. 599-603.

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Product Promise

Promise
Molecular Weight (MW)303.2
Molecular FormulaC12H19N2O2.Br
CAS No.114-80-7
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLrr
Water: 60 mg/mL (197.9 mM)rr
Ethanol: <1 mg/mL
SMILES CodeC[N+](C)(C)C1=CC=CC(OC(N(C)C)=O)=C1.[Br-]
SynonymsEustigmin bromide; Neoserine bromide
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2982 mL16.4908 mL32.9815 mL65.9631 mL
5mM0.6596 mL3.2982 mL6.5963 mL13.1926 mL
10mM0.3298 mL1.6491 mL3.2982 mL6.5963 mL
20mM0.1649 mL0.8245 mL1.6491 mL3.2982 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.