NCT-14b

This product is for research use only, not for human use. We do not sell to patients.

NCT-14b
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$850To Be Confirmed
250mg$1550To Be Confirmed
500mg$2325To Be Confirmed

Cat #: V26320 CAS #: 956154-63-5 Purity ≥ 99%

Description: NCT-14b (TCS-HDAC6; NCT14b; TCS HDAC6) is a novel, potent and selective inhibitor of histone deacetylase 6 (HDAC6) with anticancer activity.

References: Yukihiro Itoh, et al. Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007 Nov 1;50(22):5425-38.

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Molecular Weight (MW)480.70
Molecular FormulaC26H44N2O4S
CAS No.956154-63-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0803 mL10.4015 mL20.8030 mL41.6060 mL
5mM0.4161 mL2.0803 mL4.1606 mL8.3212 mL
10mM0.2080 mL1.0401 mL2.0803 mL4.1606 mL
20mM0.1040 mL0.5201 mL1.0401 mL2.0803 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.