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NBMPR

This product is for research use only, not for human use. We do not sell to patients.

NBMPR
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$430Check With Us
1g$700Check With Us
5g$2850Check With Us
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Cat #: V2200 CAS #: 38048-32-7 Purity ≥ 98%

Description: NBMPR( NBTI) is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1 (Kd = 0.1-1.0 nM, IC50s = 4.6 and 3.6 nM in rat and human, respectively).

References: Lauri Alanko, et al. Nitrobenzylthioinosine (NBMPR) binding and nucleoside transporter ENT1 mRNA expression after prolonged wakefulness and recovery sleep in the cortex and basal forebrain of rat. J Sleep Res. 2003 Dec;12(4):299-304.

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Molecular Weight (MW)419.41
Molecular FormulaC17H17N5O6S
CAS No.38048-32-7
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3843 mL11.9215 mL23.8430 mL47.6860 mL
5mM0.4769 mL2.3843 mL4.7686 mL9.5372 mL
10mM0.2384 mL1.1922 mL2.3843 mL4.7686 mL
20mM0.1192 mL0.5961 mL1.1922 mL2.3843 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.