NB-598

This product is for research use only, not for human use. We do not sell to patients.

NB-598
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$2003-6 Days
10mg$3003-6 Days
25mg$5503-6 Days
50mg$8503-6 Days
100mg$14503-6 Days
250mg$21503-6 Days

Cat #: V26263 CAS #: 131060-14-5 Purity ≥ 99%

Description: NB-598 is a novel, highly potent and competitive inhibitor of squalene epoxidase (SE), suppressing triglyceride biosynthesis through the farnesol pathway. NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

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Promise
Molecular Weight (MW)486.13
Molecular FormulaC27H32ClNOS2
CAS No.131060-14-5
SynonymsNB-598; NB 598; NB598.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0571 mL10.2853 mL20.5706 mL41.1413 mL
5mM0.4114 mL2.0571 mL4.1141 mL8.2283 mL
10mM0.2057 mL1.0285 mL2.0571 mL4.1141 mL
20mM0.1029 mL0.5143 mL1.0285 mL2.0571 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.