This product is for research use only, not for human use. We do not sell to patients.
Size | Price | Stock |
---|---|---|
5mg | $60 | 3-6 Days |
10mg | $90 | 3-6 Days |
25mg | $135 | 3-6 Days |
50mg | $200 | 3-6 Days |
100mg | $350 | 3-6 Days |
250mg | $580 | 3-6 Days |
500mg | $850 | 3-6 Days |
Cat #: V26346 CAS #: 86220-42-0 Purity ≥ 99%
Description: Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analogue of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Nafarelin may be used in the treatment of estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat central precocious puberty, and to control ovarian stimulation in IVF. It is normally delivered via a nasal spray. Nafarelin acetate is marketed by Searle (now part of Pfizer) under the brand name Synarel.
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Molecular Weight (MW) | 1400.563 |
---|---|
Molecular Formula | C68H89N17O16 |
CAS No. | 86220-42-0 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 0.7140 mL | 3.5700 mL | 7.1400 mL | 14.2800 mL |
5mM | 0.1428 mL | 0.7140 mL | 1.4280 mL | 2.8560 mL |
10mM | 0.0714 mL | 0.3570 mL | 0.7140 mL | 1.4280 mL |
20mM | 0.0357 mL | 0.1785 mL | 0.3570 mL | 0.7140 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.