N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

This product is for research use only, not for human use. We do not sell to patients.

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$220To Be Confirmed
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V39833 CAS #: 2183440-74-4 Purity ≥ 99%

Description: N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.

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Molecular Weight (MW)681.772709131241
Molecular FormulaC29H55N5O13
CAS No.2183440-74-4
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsN(AzidoPEG3)N(PEG2NHBoc)PEG3acid; N (Azido PEG3) N (PEG2 NH Boc) PEG3 acid
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4668 mL7.3338 mL14.6676 mL29.3353 mL
5mM0.2934 mL1.4668 mL2.9335 mL5.8671 mL
10mM0.1467 mL0.7334 mL1.4668 mL2.9335 mL
20mM0.0733 mL0.3667 mL0.7334 mL1.4668 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.