Home > Signaling Pathways>GPCR & G Protein>CXCR>MSX-127 (NSC-23026)
MSX-127 (NSC-23026)

This product is for research use only, not for human use. We do not sell to patients.

MSX-127 (NSC-23026)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$778Check With Us
500mg$1255Check With Us
1g$1885Check With Us
email: [email protected]        [email protected]

Cat #: V26716 CAS #: 6616-56-4 Purity ≥ 99%

Description: MSX127 (NSC23026) is a novel and potent antagonist of CXCR4 receptor with anticancer activity.

References: Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)308.37
Molecular FormulaC16H24N2O4
CAS No.6616-56-4
ProtocolIn VitroThe C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2429 mL16.2143 mL32.4286 mL64.8572 mL
5mM0.6486 mL3.2429 mL6.4857 mL12.9714 mL
10mM0.3243 mL1.6214 mL3.2429 mL6.4857 mL
20mM0.1621 mL0.8107 mL1.6214 mL3.2429 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.