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MSDC-0160 (Mitoglitazone; CAY-10415)

This product is for research use only, not for human use. We do not sell to patients.

MSDC-0160 (Mitoglitazone; CAY-10415)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$880Check With Us
500mg$1450Check With Us
1g$2175Check With Us

Cat #: V1940 CAS #: 146062-49-9 Purity ≥ 96%

Description: Mitoglitazone (MSDC-0160; CAY10415), a thiazolidinedione analog, is the prototypical mTOT(mitochondrial target of thiazolidinediones)-modulating insulin sensitizer being investigated to treat diabetes and Alzheimer's disease.

References: Rohatgi N, et al. Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets. PLoS One. 2013 May 1;8(5):e62012.

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Product Promise

Promise
Molecular Weight (MW)370.42
Molecular FormulaC19H18N2O4S
CAS No.146062-49-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLr
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=C(N1)SC(CC2=CC=C(OCC(C3=NC=C(CC)C=C3)=O)C=C2)C1=O
SynonymsMitoglitazone; CAY10415; MSDC 0160; CAY 10415; MSDC-0160; CAY-10415; CAY 10415; CAY-10415; MSDC0160; CAY10415;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6996 mL13.4982 mL26.9964 mL53.9928 mL
5mM0.5399 mL2.6996 mL5.3993 mL10.7986 mL
10mM0.2700 mL1.3498 mL2.6996 mL5.3993 mL
20mM0.1350 mL0.6749 mL1.3498 mL2.6996 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.