MRS 2578
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $760 | Check With Us |
| 1g | $1150 | Check With Us |
| 5g | $3500 | Check With Us |
: Cat #: V1302 CAS #: 711019-86-2 Purity ≥ 98%
Description: MRS2578 (MRS-2578; MRS 2578) is a potent and selective P2Y6 receptor antagonist with potentially usefulness in controlling persistent storage symptoms in obstructed patients.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 472.67 |
|---|---|
| Molecular Formula | C20H20N6S4 |
| CAS No. | 711019-86-2 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 42 mg/mL (88.8 mM)rr |
| Water:<1 mg/mLrr | |
| Ethanol:<1 mg/mL | |
| Solubility In Vivo | 30% propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL |
| Synonyms | MRS-2578; MRS2578; MRS 2578. |
| Protocol | In Vivo | MRS2578 (3 mg/kg; i.p.; for 3 days) significantly suppresses pressure overload-induced collagen deposition without affecting cardiomyocyte hypertrophy after transverse aortic constriction (TAC) |
|---|---|---|
| Animal model | 6-week-old male C57BL/6J mice | |
| Dosages | 3 mg/kg | |
| Administration | Intraperitoneal injection; daily for 3 days after TAC |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1156 mL | 10.5782 mL | 21.1564 mL | 42.3128 mL |
| 5mM | 0.4231 mL | 2.1156 mL | 4.2313 mL | 8.4626 mL |
| 10mM | 0.2116 mL | 1.0578 mL | 2.1156 mL | 4.2313 mL |
| 20mM | 0.1058 mL | 0.5289 mL | 1.0578 mL | 2.1156 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.