Moxonidine (BDF5895)

This product is for research use only, not for human use. We do not sell to patients.

Moxonidine (BDF5895)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$425Check With Us
500mg$700Check With Us
1g$1050Check With Us

Cat #: V2386 CAS #: 75438-57-2 Purity ≥ 98%

Description: Moxonidine (also known as BDF5895) is a potent and selective agonist at the imidazoline receptor subtype 1, and is used as centrally active antihypertensive agent.

References: Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.

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Product Promise

Promise
Molecular Weight (MW)241.68
Molecular FormulaC9H12ClN5O
CAS No.75438-57-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 24 mg/mL (99.3 mM)rr
Water: <1 mg/mLrr
Ethanol: 2 mg/mL (8.3 mM)
Solubility In VivoChemical Name: 4-Chloro-5-(2-imidazolin-2-ylamino)-6-methoxy-2-methylpyrimidine InChi Key: WPNJAUFVNXKLIM-UHFFFAOYSA-N InChi Code: InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15) SMILES Code: CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1
SMILES CodeCC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1
SynonymsBDF-5895; BDF5895; BDF 5895; Cynt; Nucynt; BE 5895; BE-5895; BE5895
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.1377 mL20.6885 mL41.3770 mL82.7541 mL
5mM0.8275 mL4.1377 mL8.2754 mL16.5508 mL
10mM0.4138 mL2.0689 mL4.1377 mL8.2754 mL
20mM0.2069 mL1.0344 mL2.0689 mL4.1377 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.