Montelukast Dicyclohexylamine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $450 | To Be Confirmed |
| 5g | $650 | To Be Confirmed |
| 10g | $975 | To Be Confirmed |
: Cat #: V41728 CAS #: 577953-88-9 Purity ≥ 99%
Description: Montelukast Dicyclohexylamine is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 767.50 |
|---|---|
| Molecular Formula | C47H59ClN2O3S |
| CAS No. | 577953-88-9 |
| Protocol | In Vitro | Montelukast (5 μM; 1 h) inhibits APAP (Acetaminophen) (HY-66005)-induced cell damage |
|---|---|---|
| In Vivo | Montelukast (3 mg/kg; oral gavage) protects against APAP-induced hepatotoxicity in mice | |
| Animal model | C57BL/6J mice (8-week-old; 22-25 g) are induced acute hepatic injury | |
| Dosages | 3 mg/kg | |
| Administration | Oral gavage 1 h after saline or APAP administration |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.3029 mL | 6.5147 mL | 13.0293 mL | 26.0586 mL |
| 5mM | 0.2606 mL | 1.3029 mL | 2.6059 mL | 5.2117 mL |
| 10mM | 0.1303 mL | 0.6515 mL | 1.3029 mL | 2.6059 mL |
| 20mM | 0.0651 mL | 0.3257 mL | 0.6515 mL | 1.3029 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.