MLN2480 (TAK-580)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1800 | To Be Confirmed |
| 500mg | $2350 | To Be Confirmed |
| 1g | $3525 | To Be Confirmed |
: Cat #: V2669 CAS #: 1096708-71-2 Purity ≥ 98%
Description: MLN2480 (BIIB-024; BSK1369; DAY-101; TAK-580; AMG-2112819) is an orally bioactive, potent and selective pan-Raf kinase inhibitor with potential anticancer activity.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 506.29 |
|---|---|
| Molecular Formula | C17H12Cl2F3N7O2S |
| CAS No. | 1096708-71-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (197.5 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 100 mg/mL (197.5 mM) | |
| SMILES Code | O=C(C1=CN=C([C@H](NC(C2=NC=NC(N)=C2Cl)=O)C)S1)NC3=NC=C(Cl)C(C(F)(F)F)=C3 |
| Synonyms | BIIB-024; TAK-580, AMG2112819, TAK 580, MLN2480, TAK580; AMG 2112819, BIIB024, AMG-2112819; MLN 2480, MLN-2480, BIIB 024, BIIB-024 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9752 mL | 9.8758 mL | 19.7515 mL | 39.5031 mL |
| 5mM | 0.3950 mL | 1.9752 mL | 3.9503 mL | 7.9006 mL |
| 10mM | 0.1975 mL | 0.9876 mL | 1.9752 mL | 3.9503 mL |
| 20mM | 0.0988 mL | 0.4938 mL | 0.9876 mL | 1.9752 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.