ML367
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1650 | Check With Us |
| 100mg | $2450 | Check With Us |
| 200mg | $3675 | Check With Us |
: Cat #: V25685 CAS #: 381168-77-0 Purity ≥ 99%
Description: ML367 is a novel and potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, it acts as a probe molecule that has low micromolar inhibitory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 334.32 |
|---|---|
| Molecular Formula | C19H12F2N4 |
| CAS No. | 381168-77-0 |
| Synonyms | ML367; ML-367; ML 367 |
| Protocol | In Vitro | ML367 (0-40 μM, 16 hours) inhibits FLAG-ATAD5 stabilization in HEK293T cells in the presence or absence of 20 μM 5-FUrd |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9911 mL | 14.9557 mL | 29.9115 mL | 59.8229 mL |
| 5mM | 0.5982 mL | 2.9911 mL | 5.9823 mL | 11.9646 mL |
| 10mM | 0.2991 mL | 1.4956 mL | 2.9911 mL | 5.9823 mL |
| 20mM | 0.1496 mL | 0.7478 mL | 1.4956 mL | 2.9911 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.