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ML324 (CID44143209)

This product is for research use only, not for human use. We do not sell to patients.

ML324 (CID44143209)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$610Check With Us
500mg$1050Check With Us
1g$1575Check With Us
email: [email protected]        [email protected]

Cat #: V0375 CAS #: 1222800-79-4 Purity ≥ 98%

Description: ML324 (also known as CID-44143209) is a cell-permeable and selective inhibitor of jumonji histone demethylase (JMJD2) with antiviral activity.

References: Rai G, et al. Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity.

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Molecular Weight (MW)349.43
Molecular FormulaC21H23N3O2
CAS No.1222800-79-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 43 mg/mL (123.0 mM)r
Water:<1 mg/mLr
Ethanol: 3 mg/mL (8.6 mM)
SMILES CodeO=C(NCCCN(C)C)C1=CC=C(C2=CC(O)=C3N=CC=CC3=C2)C=C1
SynonymsCID 44143209; CID-44143209; CID44143209; ML 324; ML-324; ML324
ProtocolIn VitroML324 produces a significant reduction in Aa-LPS-induced osteoclastogenesis in osteoclast progenitors.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8618 mL14.3090 mL28.6180 mL57.2361 mL
5mM0.5724 mL2.8618 mL5.7236 mL11.4472 mL
10mM0.2862 mL1.4309 mL2.8618 mL5.7236 mL
20mM0.1431 mL0.7155 mL1.4309 mL2.8618 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.